Publications

All publications can be found here on Pubmed

2024

Biotechnology Advances

Engineering aspects of lipid-based delivery systems: In vivo gene delivery, safety criteria, and translation strategies

Ismail Eş, Aneesh Thakur, Amin Mousavi Khaneghah, Camilla Foged, Lucimara Gaziola de la Torre

2024 May-June;72:108342

European Journal of Pharmaceutics and Biopharmaceutics

Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route

Melike Ongun, Abhijeet Girish Lokras, Saahil Baghel, Zhenning Shi, Signe Tandrup Schmidt, Henrik Franzyk, Thomas Rades, Federica Sebastiani, Aneesh Thakur, Camilla Foged

2024 Mar;16:114266

Journal of Colloid and Interface Science

Effect of lipid-polymer hybrid nanoparticles on the biophysical function and lateral structure of pulmonary surfactant: Mechanistic in vitro studies

You Xu, Olga Cañadas, Alejandro Alonso, Henrik Franzyk, Aneesh Thakur, Jesús Pérez-Gil, Camilla Foged

2024 Jan;654:1111-1123

2023

Vaccine Insights

European Journal of Pharmaceutics and Biopharmaceutics

Method of manufacturing CAF®09 liposomes affect immune responses induced by adjuvanted subunit proteins

Aneesh Thakur, Abishek Wadhwa, Abhijeet Lokras,  Olivia Amanda Oest Müllertz, Dennis Christensen, Henrik Franzyk, Camilla Foged

2023 Apr 12;S0939-6411(23)00085-1

Frontiers in Veterinary Science

Journal of Colloid and Interface Science

Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

Anas Aljabbari, Abhijeet Girish Lokras, Jacob Judas Kain Kirkensgaard, Thomas Rades, Henrik Franzyk, Aneesh Thakur, Yibang Zhang, Camilla Foged

2023 Mar;633:907-922

Journal of Colloid and Interface Science

Insights into the mechanisms of interaction between inhalable lipid-polymer hybrid nanoparticles and pulmonary surfactant

You Xu, Elisa Parra-Ortiz, Feng Wan, Olga Cañadas, Begoña Garcia-Alvarez, Aneesh Thakur, Henrik Franzyk, Jesús Pérez-Gil, Martin Malmsten, Camilla Foged

2023 Mar;633:511-525

2022

Molecular Pharmaceutics

Pulmonary Administration of the Liposome-Based Adjuvant CAF01: Effect of Surface Charge on Mucosal Adjuvant Function

Olivia Amanda Oest Müllertz, Peter Andersen, Dennis Christensen, Camilla Foged, Aneesh Thakur 

2022 Dec 30

International Journal of Pharmaceutics

Simultaneous quantification of multiple RNA cargos co-loaded into nanoparticle-based delivery systems

Abhijeet Lokras, Akash Chakravarty, Thomas Rades, Dennis Christensen, Henrik Franzyk, Aneesh Thakur, Camilla Foged

2022 Oct 15;626:122171

Frontiers in Drug Delivery

Optimizing the design and dosing of dry powder inhaler formulations of the cationic liposome adjuvant CAF®01 for pulmonary immunization

Aneesh Thakur, You Xu, Guillermo Cano-Garcia, Siqi Feng, Fabrice Rose, Per Gerde, Peter Andersen, Dennis Christensen, Camilla Foged

2022 Sep 07;2:973599

Frontiers in Drug Delivery

International Journal of Pharmaceutics

Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles

You Xu, Laure Harinck, Abhijeet G Lokras, Per Gerde, Ewa Selg, Carl-Olof Sjöberg, Henrik Franzyk, Aneesh Thakur, Camilla Foged

2022 Jun 10;621:121758

Pharmaceutics

Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation

Virgil Schijns, Dragomira Majhen, Peter van der Ley, Aneesh Thakur, Artur Summerfield, Rita Berisio, Cristina Nativi, Alberto Fernández-Tejada, Carmen Alvarez-Dominguez, Sveinbjörn Gizurarson, Alla Zamyatina, Antonio Molinaro, Camillo Rosano, Žiga Jakopin, Ihsan Gursel, Siobhán McClean

2022 Jun 10;621:121758

2021

Pharmaceutics

Inhaled RNA Therapeutics for Obstructive Airway Diseases: Recent Advances and Future Prospects

You Xu, Aneesh Thakur, Yibang Zhang, Camilla Foged

2021 Jan 28;13(2):177

Frontiers in Bioengineering and Biotechnology

Optimizing the Intracellular Delivery of Therapeutic Anti-inflammatory TNF-α siRNA to Activated Macrophages Using Lipidoid-Polymer Hybrid Nanoparticles

Abhijeet Lokras, Aneesh Thakur, Abishek Wadhwa, Kaushik Thanki, Henrik Franzyk, Camilla Foged

2021 Jan 14;8:601155

Methods in Molecular Biology

2020

Vaccines (Basel)

Inflammasome-Mediated Immunogenicity of Clinical and Experimental Vaccine Adjuvants

Sören Reinke, Aneesh Thakur, Cillian Gartlan, Jelena S Bezbradica, Anita Milicic

2020 Sep 22;8(3):554

Frontiers in Immunology

The Long Road Toward COVID-19 Herd Immunity: Vaccine Platform Technologies and Mass Immunization Strategies

Lea Skak Filtenborg Frederiksen, Yibang Zhang, Camilla Foged, Aneesh Thakur

2020 Jul 21;11:1817

Vaccines (Basel)

Technological Approaches for Improving Vaccination Compliance and Coverage

Céline Lemoine, Aneesh Thakur, Danina Krajišnik, Romain Guyon, Stephanie Longet, Agnieszka Razim, Sabina Górska, Ivana Pantelić, Tanja Ilić, Ines Nikolić, Ed C Lavelle, Andrzej Gamian, Snežana Savić, Anita Milicic

2020 Jun 16;8(2):304

Pharmaceutics

Opportunities and Challenges in the Delivery of mRNA-based Vaccines

Abishek Wadhwa, Anas Aljabbari, Abhijeet Lokras, Camilla Foged, Aneesh Thakur

2020 Jan 28;12(2):102

2019

International Journal of Pharmaceutics

One-pot synthesis and characterization of ovalbumin-conjugated gold nanoparticles: A comparative study of adjuvanticity against the physical mixture of ovalbumin and gold nanoparticles

Yuhua Yang, Yibang Zhang, Aneesh Thakur, Ruyan Li, Han Xu, Zhixin Wang, Mahdi Ghavami, Zhigang Tu, Hanqing Liu

2019 Nov 25;571:118704

Molecular Pharmaceutics

Design of Gadoteridol-Loaded Cationic Liposomal Adjuvant CAF01 for MRI of Lung Deposition of Intrapulmonary Administered Particles

Abishek Wadhwa, Anas Aljabbari, Abhijeet Lokras, Camilla Foged, Aneesh Thakur

2019 Nov 4;16(11):4725-4737

Pharmaceutical Research

Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation

Cypriane Dormenval, Abhijeet Lokras, Guillermo Cano-Garcia, Abishek Wadhwa, Kaushik Thanki, Fabrice Rose, Aneesh Thakur, Henrik Franzyk, Camilla Foged

2019 Aug 2;36(10):142

Journal of Immunology Research

Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies

Aneesh Thakur, Heidi Mikkelsen, Gregers Jungersen

2019 Apr 14;2019:1356540

2018

Frontiers in Immunology

Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization

Aneesh Thakur, Cristina Rodríguez-Rodríguez, Katayoun Saatchi, Fabrice Rose, Tullio Esposito, Zeynab Nosrati, Peter Andersen, Dennis Christensen, Urs O Häfeli, Camilla Foged

2018 Nov 30;9:2825

Therapeutic Delivery

Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities

Kaushik Thanki, Kevin G Blum, Aneesh Thakur, Fabrice Rose, Camilla Foged

2018 Oct;9(10):731-749

PLoS One

Targeting the Mincle and TLR3 receptor using the dual agonist cationic adjuvant formulation 9 (CAF09) induces humoral and polyfunctional memory T cell responses in calves

Aneesh Thakur, Athina Andrea, Heidi Mikkelsen, Joshua S Woodworth, Peter Andersen, Gregers Jungersen, Claus Aagaard

2018 Jul 31;13(7):e0201253

Comparative Immunology, Microbiology, and Infectious Diseases

Protein profile of FAdV-4 based on SDS-PAGE and Western blot isolated from chickens in India

Prasenjit Dhar, Aneesh Thakur, Rajesh Kumar Asrani, Vipin Katoch, Mandeep Sharma

2018 Jun;58:31-35

Vaccine

Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder

Aneesh Thakur, Pall Thor Ingvarsson, Signe Tandrup Schmidt, Fabrice Rose, Peter Andersen, Dennis Christensen, Camilla Foged

2018 May 31;36(23):3331-3339

2017

Veterinary world

Seroprevalence of viral and bacterial diseases among the bovines in Himachal Pradesh, India

Shailja Katoch, Shweta Dohru, Mandeep Sharma, Vikram Vashist, Rajesh Chahota, Prasenjit Dhar, Aneesh Thakur, Subhash Verma

2017 Dec;10(12):1421-1426

Veterinary Immunology and Immunopathology

Differences in innate and adaptive immune response traits of Pahari (Indian non-descript indigenous breed) and Jersey crossbred cattle

Subhash Verma, Aneesh Thakur, Shailja Katoch, Chander Shekhar, Aasim Habib Wani, Sandeep Kumar, Shweta Dohroo, Geetanjali Singh, Mandeep Sharma

2017 Oct;192:20-27

2016

Veterinary World

First detection of canine parvovirus type 2b from diarrheic dogs in Himachal Pradesh

Shalini Sharma, Prasenjit Dhar, Aneesh Thakur, Vivek Sharma, Mandeep Sharma

2016 Sep;9(9):964-969

2013

Veterinary Immunology and Immunopathology

Increasing the ex vivo antigen-specific IFN-γ production in subpopulations of T cells and NKp46+ cells by anti-CD28, anti-CD49d and recombinant IL-12 costimulation in cattle vaccinated with recombinant proteins from Mycobacterium avium subspecies paratuberculosis

Aneesh Thakur, Ulla Riber, William C Davis, Gregers Jungersen

2013 Oct 1;155(4):276-83

Clinical and Vaccine Immunology

2012

Vaccine

Immune markers and correlates of protection for vaccine induced immune responses

Aneesh Thakur, Lasse E Pedersen, Gregers Jungersen

2012 Jul 13;30(33):4907-20

Indian Journal of Microbiology

Detection of Mycobacterium bovis and Mycobacterium tuberculosis from Cattle: Possible Public Health Relevance

Aneesh Thakur, Mandeep Sharma, Vipin C Katoch, Prasenjit Dhar, R C Katoch

2012 Jun;52(2):289-91

Veterinary Immunology and Immunopathology

Characterization of the long-term immune response to vaccination against Mycobacterium avium subsp. paratuberculosis in Danish dairy cows

Vibeke Thulstrup Thomsen, Søren Saxmose Nielsen, Aneesh Thakur, Gregers Jungersen

2012 Jan 15;145(1-2):316-22

2008

Indian Journal of Microbiology

Isolation of Moraxella bovis from frozen bovine semen and determination of microbial load

Abhishek Gandhi, Mandeep Sharma, Prasenjit Dhar, Vipin Katoch, Aneesh Thakur, and Rajinder Kumar

2008 Sep;48(3):405-7

Book Chapters

Springer

Lipid Nanoparticle-Mediated Delivery of Therapeutic and Prophylactic mRNA: Immune Activation by Ionizable Cationic Lipids

Ongun, M., Lokras, A.G., Foged, C., Thakur, A. (2022). Lipid Nanoparticle-Mediated Delivery of Therapeutic and Prophylactic mRNA: Immune Activation by Ionizable Cationic Lipids. In: Jurga, S., Barciszewski, J. (eds) Messenger RNA Therapeutics. RNA Technologies, vol 13. Springer, Cham.

Department of Science Education

Restructuring the PhD course in Drug Delivery for a better alignment and congruence

Thakur A. (2022)Restructuring the PhD course in Drug Delivery for a better alignment and congruence. In: Improving University Science Teaching and Learning – Pedagogical Projects 2022. Department of Science Education, University of Copenhagen, Denmark. 17:215-229.

Elsevier

Adjuvants, immunomodulators, and adaptogens

Milicic, A., Reinke, S., Fergusson, J., Lindblad, E. B., Hu, K., Thakur, A., Corby, G., Longet, S., Górska, S., Razim, A., Morein, B., Luchner, M., Christensen, D., Mrenoshki, S., Ceylan, S. E., Gizurarson, S., & Ugwu, M. C. (2022). Adjuvants, immunomodulators, and adaptogens. In Vaccinology and Methods in Vaccine Research (pp. 223-280). Elsevier. https://doi.org/10.1016/B978-0-323-91146-7.00009-3

Springer

Engineering of Solid Dosage Forms of siRNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles Using a Quality-by-Design Approach

Lokras, A., Foged, C., Thakur, A. (2021). Engineering of Solid Dosage Forms of siRNA-Loaded Lipidoid–Polymer Hybrid Nanoparticles Using a Quality-by-Design Approach. In: Ditzel, H.J., Tuttolomondo, M., Kauppinen, S. (eds) Design and Delivery of SiRNA Therapeutics. Methods in Molecular Biology, vol 2282. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1298-9_9

Elsevier

Nanoparticles for mucosal vaccine delivery

Thakur, A., & Foged, C. (2020). Nanoparticles for mucosal vaccine delivery. In M. Mozafari (Ed.), Nanoengineered Biomaterials for Advanced Drug Delivery (1 ed.). Elsevier.